Loyola University Stritch School of Medicine, Maywood, IL.
Loyola University Chicago Stritch School of Medicine, Maywood, IL.
Psychosomatics. 2018 Sep-Oct;59(5):512-516. doi: 10.1016/j.psym.2018.02.001. Epub 2018 Feb 13.
The present case report describes a case of serotonin syndrome which developed post-septal myectomy in a patient with hypertrophic cardiomyopathy. This case contributes to an emerging awareness of serotonin syndrome in the context of prescribed serotonergic agents, such as SSRIs, and triggered by the addition of fentanyl and methylene blue, particularly in conjunction cardiological procedures. Clinicians should be aware of such interactions which increase the emergence of the serotonin syndrome and the appropriate management of comorbid delirium post-serotonin syndrome.
本病例报告描述了一例肥厚型心肌病患者行间隔心肌切除术(septal myectomy)后出现的血清素综合征(serotonin syndrome)。该病例引起了人们对处方中使用血清素能药物(如 SSRIs)以及芬太尼和亚甲蓝(methylene blue)等药物联合使用时出现血清素综合征的关注,尤其是在心脏科手术过程中。临床医生应该注意这些相互作用,这些相互作用会增加血清素综合征的发生,并适当处理血清素综合征后的共病性谵妄。