de la Grandmaison Geoffroy Lorin, Durigon Michel
Department of Pathology, Raymond Poincarè Hospital, Paris-Quest University, Garches, France.
Am J Forensic Med Pathol. 2002 Sep;23(3):257-9. doi: 10.1097/01.PAF.0000025639.29179.1A.
Pulmonary embolism can be observed at any age, but it occurs very rarely in the infant. The authors report the case of a 12-month-old boy who suddenly died during clinical improvement of gastroenteritis associated with otitis. Autopsy showed signs of dehydration and acute left pulmonary embolism, which was the cause of death. Thrombosis of the inferior vena cava extending into renal veins was seen. In this case, plasma hyperosmolality caused by dehydration might have favored the formation of venous thromboses. The various risk factors of pulmonary embolism in the child are discussed, including genetic factors.
肺栓塞可发生于任何年龄，但在婴儿中极为罕见。作者报告了一例12个月大男童的病例，该患儿在与中耳炎相关的肠胃炎临床症状改善期间突然死亡。尸检显示有脱水迹象及急性左肺栓塞，这是死亡原因。可见下腔静脉血栓形成并延伸至肾静脉。在该病例中，脱水引起的血浆高渗状态可能促进了静脉血栓的形成。本文讨论了儿童肺栓塞的各种危险因素，包括遗传因素。
