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一种新的地中海实蝇特异性44碱基对着丝粒周围重复序列的鉴定与部分特征分析。

Identification and partial characterization of a new Ceratitis capitata-specific 44-bp pericentromeric repeat.

作者信息

Stratikopoulos E E, Augustinos A A, Gariou-Papalexiou A, Zacharopoulou A, Mathiopoulos K D

机构信息

Department of Biology, Division of Genetics, Cell and Developmental Biology, University of Patras, Greece.

出版信息

Chromosome Res. 2002;10(4):287-95. doi: 10.1023/a:1016567624117.

DOI:10.1023/a:1016567624117
PMID:12199142
Abstract

Tandem satellite DNA repeats are often associated with centromeres. In spite of their importance in the organization of the centromere, they do not seem to be broadly conserved among species and their role is still unclear. Here we report the identification of a new 44-bp tandem pericentromeric repeat from the medfly, Ceratitis capitata. The repeat is specific to this insect and is not found in any of the other closely related species tested. It localizes in four out of its five autosomes and in the X chromosome. It is organized in long arrays, interspersed by transposable elements and other less well-defined sequence motifs.

摘要

串联卫星DNA重复序列通常与着丝粒相关。尽管它们在着丝粒的组织中很重要,但它们在物种间似乎没有广泛保守,其作用仍不清楚。在这里,我们报告了从地中海实蝇(Ceratitis capitata)中鉴定出一种新的44碱基对串联着丝粒周围重复序列。该重复序列是这种昆虫特有的,在所测试的任何其他近缘物种中都未发现。它定位于其五条常染色体中的四条以及X染色体上。它以长阵列形式组织,由转座元件和其他定义不太明确的序列基序穿插其中。

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