Kan Chung-Ben, Wang Jih-Shiuan, Lee Chiu-Yang, Yu Tarng-Jenn, Huang Cheng-Hsiung, Shih Chun-Tse, Yung Ming-Chi, Lai Shiau-Ting
Department of Surgery, Chia-Yi Christian Hospital, ROC.
Zhonghua Yi Xue Za Zhi (Taipei). 2002 Jun;65(6):247-53.
"Off-pump" coronary artery bypass grafting (OPCABG) became more popular in recent years for its potential advantages of reducing perioperative morbidity related to cardiopulmonary bypass (CPB). We retrospectively analyzed the early results of multivessel OPCABG to compare them with conventional CABG under CPB.
From April 2000 to Oct 2000, 15 patients received multivessel OPCABG (group A). CTS or Octopus II stabilizer was used with coronary anastomosis. "Auto-perfusion system" was used at late stage of our series for myocardial protection in the procedure. At the same time, patients who received primary isolated CABG under CPB were compared as control (group B).
There was no operative mortality or major morbidity in the group of multivessel OPCABG. Two patients who failed multivessel OPCABG due to hemodynamics compromise were converted to conventional CABG under CPB uneventfully. The amount of operative blood loss and donor blood transfusion, the duration of postoperative mechanical ventilation support, the mean intensive care unit stay and postoperative hospital stay were less in group A.
Multivessel OPCABG is feasible in surgical techniques in selected patient. It is associated with minimal operative mortality and morbidity partly because of obviating the adverse effect of CPB. Prospective study with long-term follow-up is needed to better define the role of OPCABG.
近年来,“非体外循环”冠状动脉旁路移植术(OPCABG)因其在降低与体外循环(CPB)相关的围手术期发病率方面的潜在优势而越来越受欢迎。我们回顾性分析了多支血管OPCABG的早期结果,以与CPB下的传统CABG进行比较。
2000年4月至2000年10月,15例患者接受了多支血管OPCABG(A组)。冠状动脉吻合时使用了CTS或Octopus II稳定器。在我们系列研究的后期,“自动灌注系统”用于术中心肌保护。同时,将接受CPB下初次单纯CABG的患者作为对照组(B组)。
多支血管OPCABG组无手术死亡或严重并发症。2例因血流动力学不稳定而OPCABG失败的患者顺利转为CPB下的传统CABG。A组的手术失血量、供体输血量、术后机械通气支持时间、平均重症监护病房停留时间和术后住院时间均较少。
多支血管OPCABG在选定患者的手术技术中是可行的。它与最低的手术死亡率和发病率相关,部分原因是避免了CPB的不良影响。需要进行长期随访的前瞻性研究,以更好地确定OPCABG的作用。