Alemayehu Berhanu, Aubert Ronald E, Feifer Richard A, Paul Lester D
Clinical Analysis and Outcomes Research, Medco Health Solutions, Inc., 100 Parsons Pond Drive, Franklin Lakes, NJ 07417-2603, USA.
Value Health. 2002 Sep-Oct;5(5):437-42. doi: 10.1046/J.1524-4733.2002.55151.x.
The St. George's Respiratory Questionnaire (SGRQ) has been validated and widely used in assessing quality of life among patients with chronic obstructive pulmonary disease (COPD), but it is time-consuming and complicated to score. A more concise instrument, the Airways Questionnaire (AQ), was developed to measure quality of life (QoL) among patients with asthma and COPD. The shorter version of this instrument has 20 items (AQ20) and the longer version has 30 items (AQ30). The purpose of this study was to determine the relationship between QoL scores measured by the AQ20/30 or the SGRQ scale and utilization of health-care services by COPD patients and to evaluate the comparative advantage of any one of these instruments in measuring the QoL of COPD patients.
Results from a survey of 1000 patients participating in a pilot COPD health management program were used for this analysis. A total of 303 patients completed both the AQ20/30 and the SGRQ questionnaires. Logistic regression models were used to analyze the relationship between utilization of health care services and QoL scores while controlling for a set of covariates. Spearman's rank correlation was used to determine whether the AQ30 and the SGRQ scores for symptoms, activity, and impact, and the overall scores were correlated.
The regression results demonstrate that there is a strong relationship between quality-of-life scores and health-care utilization variables. Moreover, the degree of association between the AQ20/30 scores and utilization variables and the SGRQ and utilization variables are comparable. Both the AQ20 and the AQ30 were highly correlated with the overall SGRQ score and with symptoms, activity, and impact component scores.
The AQ20/30 and the SGRQ scores are comparable in terms of measuring QoL in COPD patients and are equally useful in determining the association between utilization of health-care services and QoL.
圣乔治呼吸问卷（SGRQ）已得到验证，并广泛用于评估慢性阻塞性肺疾病（COPD）患者的生活质量，但该问卷评分耗时且复杂。一种更简洁的工具——气道问卷（AQ）被开发出来，用于测量哮喘和COPD患者的生活质量。该工具的较短版本有20个条目（AQ20），较长版本有30个条目（AQ30）。本研究的目的是确定通过AQ20/30或SGRQ量表测量的生活质量得分与COPD患者医疗服务利用之间的关系，并评估这些工具在测量COPD患者生活质量方面的比较优势。
本分析使用了对1000名参与COPD健康管理试点项目患者的调查结果。共有303名患者同时完成了AQ20/30和SGRQ问卷。在控制一组协变量的同时，使用逻辑回归模型分析医疗服务利用与生活质量得分之间的关系。使用Spearman等级相关性来确定AQ30和SGRQ在症状、活动和影响方面的得分以及总体得分是否相关。
回归结果表明，生活质量得分与医疗服务利用变量之间存在密切关系。此外，AQ20/30得分与利用变量之间的关联程度以及SGRQ与利用变量之间的关联程度具有可比性。AQ20和AQ30与SGRQ总体得分以及症状、活动和影响分量得分均高度相关。
在测量COPD患者的生活质量方面，AQ20/30得分与SGRQ得分具有可比性，并且在确定医疗服务利用与生活质量之间的关联方面同样有用。
