Eisenberg Dan L, Toris Carol B, Camras Carl B
Shepherd Eye Center, Las Vegas, NV, USA.
Surv Ophthalmol. 2002 Aug;47 Suppl 1:S105-15. doi: 10.1016/s0039-6257(02)00327-2.
Bimatoprost (Lumigan [Allergan, Inc, Irvine CA]) and travoprost (Travatan [Alcon, Ft Worth, TX]) are two new intraocular pressure (IOP)-lowering drugs for use in patients with glaucoma and ocular hypertension. This review evaluates recent studies comparing these new drugs with timolol and with latanoprost. In each study, the statistical analyses support the conclusion that these agents were more effective than timolol and as effective as latanoprost in terms of their ability to reduce IOP. The side effect profiles for bimatoprost, latanoprost, and travoprost were similar, but with statistically higher occurrences of hyperemia and eyelash growth for bimatoprost or travoprost versus latanoprost or timolol.
比马前列素(卢美根[爱尔康公司,加利福尼亚州欧文市])和曲伏前列素(苏为坦[爱尔康公司,得克萨斯州沃思堡])是两种用于青光眼和高眼压症患者的新型降眼压药物。本综述评估了近期将这些新药与噻吗洛尔和拉坦前列素进行比较的研究。在每项研究中,统计分析均支持以下结论:就降低眼压的能力而言,这些药物比噻吗洛尔更有效,且与拉坦前列素效果相当。比马前列素、拉坦前列素和曲伏前列素的副作用情况相似,但与拉坦前列素或噻吗洛尔相比,比马前列素或曲伏前列素发生充血和睫毛生长的几率在统计学上更高。