Lee You Kyung, Lee Ji Young, Moon Jung Il, Park Myoung Hee
Department of Ophthalmology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #62 Yeouido-dong, Yeoungdeungpo-gu, Seoul, 150-713, Korea.
Jpn J Ophthalmol. 2014 Nov;58(6):496-502. doi: 10.1007/s10384-014-0343-3. Epub 2014 Aug 29.
To evaluate the effectiveness of the ICare rebound tonometer in patients with overestimated intraocular pressure (IOP) due to tight orbit syndrome and to identify factors affecting the development of tight orbit syndrome in glaucoma patients.
We investigated 84 eyes in 84 glaucoma patients, of which 14 eyes were classified in the tight orbit syndrome group and 70 eyes in the control group. IOP was measured using the ICare tonometer and the Goldmann applanation tonometer (GAT). The demographic data, medical histories, ocular histories, and detailed ocular drug histories of the two groups were compared to identify factors contributing to the development of tight orbit syndrome.
In the tight orbit syndrome group, the ICare tonometer significantly underestimated the IOP by approximately 8.6 mmHg compared with the GAT. In the control group, the IOP readings of the GAT and the ICare tonometer did not differ significantly. Bland-Altman analysis showed that the mean difference between measurements taken using the GAT and those taken using the ICare tonometer was 2.5 ± 6.3 mmHg. The difference between the GAT and ICare tonometer measurements was greater in the tight orbit syndrome group (8.6 ± 5.3 mmHg) than in the control group (1.3 ± 2.7 mmHg). Multivariate regression analysis revealed that only the use of prostaglandin analogs (PGAs) was associated with the development of tight orbit syndrome.
The ICare tonometer is a suitable alternative device for use in patients with tight orbit syndrome in whom the IOP may be overestimated with the GAT. The prolonged use of PGAs is significantly associated with the development of tight orbit syndrome.
评估Icare回弹式眼压计在因眼眶紧绷综合征导致眼压（IOP）高估患者中的有效性，并确定影响青光眼患者眼眶紧绷综合征发生发展的因素。
我们调查了84例青光眼患者的84只眼，其中14只眼被归入眼眶紧绷综合征组，70只眼为对照组。使用Icare眼压计和Goldmann压平眼压计（GAT）测量眼压。比较两组的人口统计学数据、病史、眼部病史和详细的眼部用药史，以确定导致眼眶紧绷综合征发生发展的因素。
在眼眶紧绷综合征组中，与GAT相比，Icare眼压计显著低估眼压约8.6 mmHg。在对照组中，GAT和Icare眼压计的眼压读数无显著差异。Bland-Altman分析显示，GAT测量值与Icare眼压计测量值之间的平均差异为2.5±6.3 mmHg。眼眶紧绷综合征组中GAT与Icare眼压计测量值之间的差异（8.6±5.3 mmHg）大于对照组（1.3±2.7 mmHg）。多因素回归分析显示，仅使用前列腺素类似物（PGA）与眼眶紧绷综合征的发生有关。
对于眼眶紧绷综合征患者，Icare眼压计是一种合适的替代设备，这类患者使用GAT时眼压可能被高估。长期使用PGA与眼眶紧绷综合征的发生显著相关。
