Pichler H, Kofler K, Ludvik W, Porpaczy P, Scherzer W
Acta Med Austriaca. 1975;2(5):170-6.
Thirtyeight patients with a chronic urinary infection (definitions see methods) were treated for 3 months with Trimethoprim-Sulfametrol. During therapy in 19 (70%) out of 27 patients without obstruction in the urinary tract infection could be eliminated. In 3 (27%) out of 11 patients with obstruction in the urinary tract infection was also eliminated. In 2 (18%) of these 11 patients the causative organisms changed to resistant strains. In 2 patients (10%) resp. in one patient without obstruction and one with obstruction in the urinary tract the infection recurred within the follow up of 3 months.
38例慢性尿路感染患者（定义见方法部分）接受了甲氧苄啶-磺胺甲恶唑治疗3个月。在治疗期间，27例无尿路梗阻的患者中有19例（70%）尿路感染得以消除。11例有尿路梗阻的患者中有3例（27%）尿路感染也得以消除。在这11例患者中有2例（18%）病原菌转变为耐药菌株。在2例患者（10%）中，分别是1例无尿路梗阻患者和1例有尿路梗阻患者，在3个月的随访期内感染复发。
