Pirisino R, Pecori Vettori L
Farmaco Sci. 1979 Sep;34(9):802-7.
The paper reports the pharmacological activity in vitro and in vivo of a series of pyrazolo[1,5-a]pyrimidine derivatives. Some of these compounds have proved to be active in decreasing the body temperature. They are also very active inhibitors of the guinea-pig lung prostaglandin-sintetase.
该论文报道了一系列吡唑并[1,5-a]嘧啶衍生物的体外和体内药理活性。其中一些化合物已被证明具有降低体温的活性。它们也是豚鼠肺前列腺素合成酶的强效抑制剂。