脑脊液中丙型肝炎病毒序列的检测与分析。
Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid.
作者信息
Laskus Tomasz, Radkowski Marek, Bednarska Agnieszka, Wilkinson Jeffrey, Adair Debra, Nowicki Marek, Nikolopoulou Georgia B, Vargas Hugo, Rakela Jorge
机构信息
Division of Transplantation Medicine, Mayo Clinic, Scottsdale, Arizona 85259, USA.
出版信息
J Virol. 2002 Oct;76(19):10064-8. doi: 10.1128/jvi.76.19.10064-10068.2002.
Abstract
Hepatitis C virus (HCV) sequences were detected in cerebrospinal fluid (CSF) in 8 of 13 HCV-positive patients. In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain.
摘要
在13例丙型肝炎病毒（HCV）阳性患者中，有8例患者的脑脊液（CSF）中检测到了HCV序列。在4例血清和外周血单个核细胞（PBMC）中携带不同病毒株的患者中，脑脊液来源的病毒与PBMC中发现的病毒相似，这表明PBMC可能将HCV带入大脑。
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