一家康复中心因环境污染发生了诺沃克样杯状病毒（NLV）肠胃炎的长期暴发。
A prolonged outbreak of Norwalk-like calicivirus (NLV) gastroenteritis in a rehabilitation centre due to environmental contamination.
作者信息
Kuusi M, Nuorti J P, Maunula L, Minh Tran N N, Ratia M, Karlsson J, von Bonsdorff C H
机构信息
Department of Infectious Disease Epidemiology, National Public Health Institute, Helsinki, Finland.
出版信息
Epidemiol Infect. 2002 Aug;129(1):133-8. doi: 10.1017/s0950268802007276.
An outbreak of Norwalk-like calicivirus (NLV) gastroenteritis occurred in a rehabilitation centre in southern Finland between December 1999 and February 2000. An epidemiological investigation was conducted to determine the source and extent of the outbreak. More than 300 guests and staff members became ill during the outbreak. No food or activity in the centre could be linked epidemiologically to illness. NLV genogroup II was detected by RT-PCR in stool samples of symptomatic guests and employees. All strains reacted similarly with the microplate hybridization probe panel and showed the same nucleotide sequence, indicating that they represented the same NLV strain. Food and water samples were negative for NLV, whereas NLV was detected in three environmental specimens. The strains from patients and environment were identical based on microplate hybridization probes, suggesting that environmental contamination may have been important for the spread of calicivirus and the protracted course of the outbreak.
1999年12月至2000年2月期间，芬兰南部一家康复中心爆发了诺如样杯状病毒（NLV）肠胃炎。开展了一项流行病学调查以确定此次疫情的源头和范围。疫情期间，300多名宾客和工作人员患病。该中心的任何食物或活动在流行病学上均与疾病无关。通过逆转录聚合酶链反应（RT-PCR）在有症状宾客和员工的粪便样本中检测到了NLV基因II群。所有菌株与微孔板杂交探针组反应相似，并显示出相同核苷酸序列，表明它们代表同一NLV菌株。食物和水样的NLV检测呈阴性，而在三个环境样本中检测到了NLV。基于微孔板杂交探针，患者和环境中的菌株相同，这表明环境污染可能对杯状病毒传播及疫情的迁延过程起了重要作用。
Zotero 插件