Fabrizi G, Zannoni G F, Lopez L I, Massi G
Department of Dermatology, Catholic University Medical School, Rome, Italy.
Eur J Gynaecol Oncol. 2002;23(4):323-4.
We report a case of a 24-year-old woman with multiple pigmented lesions on her vulva. Histologically the lesions showed a heterogeneous pattern: the majority consisted of melanoma in situ and invasive melanoma; in a few lesions a much less clear-cut picture was found with only melanocytic dysplasia of various degrees. Our case shows the relationship between anomalous melanocytic proliferation of the vulva and vulvar melanoma and underlines the necessity of a thorough check of all melanocytic vulvar lesions also in young patients.
我们报告一例24岁女性,其外阴有多处色素沉着病变。组织学上,病变呈现出异质性模式:大多数病变由原位黑色素瘤和浸润性黑色素瘤组成;在少数病变中,发现的情况不太明确,仅有不同程度的黑素细胞发育异常。我们的病例显示了外阴黑素细胞异常增殖与外阴黑色素瘤之间的关系,并强调了即使是年轻患者,也有必要对所有外阴黑素细胞病变进行全面检查。