Young H, Harris A B, Urquhart D, Robertson D H
Scott Med J. 1979 Oct;24(4):302-6. doi: 10.1177/003693307902400410.
The number of gonoccal infections detected by each of three sets of diagnostic cultures from the urethra, cervix, rectum and occasionally the throat, were calculated for 1976 when Thayer Martin (TM) medium was used and for 1977 when Modified New York City (MNYC) medium was used. In 1977, 98.7 per cent (451/457) of the total infections diagnosed were confirmed by culture compared with 88.3 per cent (324/367) of infections diagnosed in 1976 (P less than 0.001). The first set of diagnostic tests detected 97.6 per cent (440/451) of culture-positive infections in 1977 compared with only 88.9 per cent (228/324) in 1976 (P less than 0.001). The efficiency of screening with a single endocervical culture was also calculated. This procedure would have detected 90.2 per cent (407/451) of culture-positive infections in 1977 when MNYC medium was used compared with only 78.1 per cent (253/324) in 1976 when TM medium was used (P less than 0.001). It is suggested that the statistically significant improvement in the culture results for 1977 resulted from the introduction of MNYC medium since all other diagnostic procedures were identical to those in 1976. Other advantages associated with the use of MNYC medium are discussed.
计算了1976年使用塞耶-马丁（TM）培养基时以及1977年使用改良纽约市（MNYC）培养基时，通过对尿道、宫颈、直肠以及偶尔对咽喉进行的三组诊断性培养所检测到的淋球菌感染数量。1977年，经培养确诊的感染病例占全部确诊感染病例的98.7%（451/457），而1976年这一比例为88.3%（324/367）（P＜0.001）。1977年，第一组诊断检测发现了97.6%（440/451）的培养阳性感染病例，而1976年这一比例仅为88.9%（228/324）（P＜0.001）。还计算了单次宫颈内膜培养的筛查效率。1977年使用MNYC培养基时，该方法能检测到90.2%（407/451）的培养阳性感染病例，而1976年使用TM培养基时这一比例仅为78.1%（253/324）（P＜0.001）。有人认为，1977年培养结果在统计学上的显著改善是由于引入了MNYC培养基，因为所有其他诊断程序与1976年相同。文中还讨论了使用MNYC培养基的其他优点。
