Curtis P D, Pooler R L, Richmond M E, Miller L A, Mattfeld G F, Quimby F W
Department of Natural Resources, Cornell University, Ithaca, NY 14853, USA.
Reprod Suppl. 2002;60:131-41.
Fawning rates and mating behaviour were compared between white-tailed deer (Odocoileus virginianus) treated with GnRH and porcine zona pellucida (PZP) immunocontraceptive vaccines from 1997 to 2000. Female deer from a herd of 102 deer at Seneca Army Depot, near Romulus, New York, were treated with prime and booster injections of PZP (n = 22) or GnRH vaccine (n = 32), or remained untreated as controls (n = 34). During the summers after booster treatment, observed fawning rates for adult female deer were similar for both PZP-treated (0.10-0.11 fawns per female) and GnRH-treated (0.13-0.22 fawns per female) female deer, and were significantly lower (t = -8.93 and t = -9.73; P < or = 0.0005, respectively) than those observed for control female deer (1.22-1.38 fawns per female). During the second (0.36 fawns per female) and third summers (0.61 fawns per female) after the last booster injection, GnRH-treated female deer still produced significantly fewer fawns than did the controls (1.38 and 1.31 fawns per female, respectively). In one breeding season after treatment, five of 18 (28%) females vaccinated with PZP produced fawns, similar to the rate for GnRH-treated females (29%). In addition, females treated with GnRH had fewer oestrous cycles per female (0.06, P < or = 0.05) than did either control (0.22 cycles per female) or PZP-treated deer (0.36 cycles per female). Initial PZP treatment followed by a booster dose 5-7 months later reduced fawn production and prolonged the breeding season as females repeatedly returned to oestrus, similar to results reported in other studies.
1997年至2000年期间，对接受促性腺激素释放激素（GnRH）和猪透明带（PZP）免疫避孕疫苗治疗的白尾鹿（弗吉尼亚鹿）的求偶率和交配行为进行了比较。纽约州罗穆卢斯附近塞内卡陆军仓库的一群102只鹿中的雌性鹿，接受了PZP（n = 22）或GnRH疫苗（n = 32）的初次和加强注射，或作为对照不接受治疗（n = 34）。在加强治疗后的夏季，接受PZP治疗的成年雌性鹿（每只雌性0.10 - 0.11只幼鹿）和接受GnRH治疗的成年雌性鹿（每只雌性0.13 - 0.22只幼鹿）的观察到的产仔率相似，且均显著低于对照雌性鹿（每只雌性1.22 - 1.38只幼鹿）（t分别为 - 8.93和 - 9.73；P≤0.0005）。在最后一次加强注射后的第二个夏季（每只雌性0.36只幼鹿）和第三个夏季（每只雌性0.61只幼鹿），接受GnRH治疗的雌性鹿产仔数仍显著少于对照鹿（分别为每只雌性1.38只和1.31只幼鹿）。在治疗后的一个繁殖季节，18只接受PZP疫苗接种的雌性鹿中有5只（28%）产仔，与接受GnRH治疗的雌性鹿的产仔率（29%）相似。此外，接受GnRH治疗的雌性鹿每只的发情周期数（0.06，P≤0.05）少于对照鹿（每只雌性0.22个周期）或接受PZP治疗的鹿（每只雌性0.36个周期）。最初进行PZP治疗，5 - 7个月后进行加强剂量注射，可减少幼鹿数量并延长繁殖季节，因为雌性鹿会反复发情，这与其他研究报告的结果相似。
