Shideler S E, Stoops M A, Gee N A, Howell J A, Lasley B L
Reprod Suppl. 2002;60:169-76.
The potential for the application of porcine zona pellucida (PZP) immunocontraception in wildlife population management has been tested over a 15 year period and promises to provide a useful wildlife management tool. These studies have provided evidence indicating that the use of PZP immunocontraception in wildlife: (i) is effective at both the physiological and population level (Liu et al., 1989; Kirkpatrick et al., 1996; Turner et al., this supplement); (ii) is deliverable by remote means (Kirkpatrick et al., 1990; Shideler, 2000); (iii) is safe in pregnant animals (Kirkpatrick and Turner, this supplement); (iv) is reversible (Kirkpatrick et al., 1991; Kirkpatrick and Turner, this supplement); (v) results in no long-term debilitating health problems (Kirkpatrick et al., 1995; Turner and Kirkpatrick, this supplement); (vi) has no implications for passage through the food chain (Harlow and Lane, 1988); and (vii) is reasonably inexpensive (J. F. Kirkpatrick, personal communication). This report presents the results of a 5 year study in tule elk (Cervus elaphus nannodes), 3 years of which were on the application of PZP immunocontraception to an expanding elk population living in a wilderness area of Point Reyes National Seashore in Marin County, CA, where hunting is not allowed and culling is not publicly acceptable.
猪透明带（PZP）免疫避孕法在野生动物种群管理中的应用潜力已在15年的时间里得到了测试，并有望成为一种有用的野生动物管理工具。这些研究提供的证据表明，在野生动物中使用PZP免疫避孕法：（i）在生理和种群水平上均有效（Liu等人，1989年；Kirkpatrick等人，1996年；Turner等人，本增刊）；（ii）可通过远程方式实施（Kirkpatrick等人，1990年；Shideler，2000年）；（iii）对怀孕动物安全（Kirkpatrick和Turner，本增刊）；（iv）具有可逆性（Kirkpatrick等人，1991年；Kirkpatrick和Turner，本增刊）；（v）不会导致长期的健康问题（Kirkpatrick等人，1995年；Turner和Kirkpatrick，本增刊）；（vi）对食物链没有影响（Harlow和Lane，1988年）；以及（vii）成本相对较低（J.F.Kirkpatrick，个人交流）。本报告介绍了一项针对图勒麋鹿（Cervus elaphus nannodes）的为期5年的研究结果，其中3年研究了在加利福尼亚州马林县雷耶斯角国家海岸荒野地区不断增长的麋鹿种群中应用PZP免疫避孕法的情况，该地区不允许狩猎且公众不接受捕杀。
