Fiske Janice, Griffiths Janet, Thompson Shelagh
Guy's, King's and St Thomas' Dental Institute of King's College, London.
Dent Update. 2002 Jul-Aug;29(6):273-83. doi: 10.12968/denu.2002.29.6.273.
Multiple sclerosis is a complex neurological condition affecting sensory and motor nerve transmission. Its progression and symptoms are unpredictable and vary from person to person as well as over time. Common early symptoms include visual disturbances, facial pain or trigeminal neuralgia and paraesthesia or numbness of feet, legs, hands and arms. These, plus symptoms of spasticity, spasms, tremor, fatigue, depression and progressive disability, impact on the individual's ability to maintain oral health, cope with dental treatment and access dental services. Also, many of the medications used in the symptomatic management of the condition have the potential to cause dry mouth and associated oral disease. There is no cure for multiple sclerosis, and treatment focuses on prevention of disability and maintenance of quality of life. Increasingly a multi-disciplinary team approach is used where the individual, if appropriate his/her carer, and the specialist nurse are key figures. The dental team plays an essential role in ensuring that oral health impacts positively on general health.
多发性硬化症是一种影响感觉和运动神经传导的复杂神经系统疾病。其进展和症状不可预测，因人而异，且会随时间变化。常见的早期症状包括视觉障碍、面部疼痛或三叉神经痛以及足部、腿部、手部和手臂的感觉异常或麻木。这些症状，再加上痉挛、抽搐、震颤、疲劳、抑郁和进行性残疾等症状，会影响个体维持口腔健康、应对牙科治疗以及获得牙科服务的能力。此外，用于该疾病症状管理的许多药物都有可能导致口干及相关口腔疾病。多发性硬化症无法治愈，治疗重点在于预防残疾和维持生活质量。越来越多地采用多学科团队方法，其中患者（如适用，其护理人员）和专科护士是关键人物。牙科团队在确保口腔健康对整体健康产生积极影响方面发挥着重要作用。
