Marrie R A, Goldman M
Department of Neurology, Cleveland Clinic, Cleveland, OH, USA.
Mult Scler. 2007 Nov;13(9):1176-82. doi: 10.1177/1352458507078388. Epub 2007 Jul 10.
Researchers increasingly use self-reported health status assessments, but these require validation. Performance Scales (PS) is a self-report measure for multiple sclerosis (MS)-associated disability, assessing mobility, bowel/bladder, fatigue, sensory, vision, cognition, spasticity and hand function. The criterion validity of the total PS score was established using the Expanded Disability Status Scale (EDSS), but the construct and criterion validity of the individual subscales have not been established. We assessed the criterion and construct validity of the PS subscales. Forty-four patients with MS completed PS, and these criterion measurements: neurological examination (EDSS), the Multiple Sclerosis Functional Composite (MSFC), contrast acuity testing, and the Multiple Sclerosis Quality of Life Inventory. We assessed criterion and construct validity with Spearman rank correlations between PS subscales and the other measurements. PS correlated with the MSFC (r=-0.58, P<0.0001). The mobility, hand, vision, fatigue and bladder subscales correlated with their criterion measures (r=0.59-0.77, P<0.0001). The sensory subscale correlated weakly with the sensory functional system score (r=0.39, P=0.01 ), and the cognitive subscale did not correlate with the PASAT (r=-0.17, P=0.26). This study supports the criterion and construct validity of PS overall, and its mobility, hand, vision, fatigue, and bladder subscales. Further assessment of the cognitive, sensory and spasticity subscales is needed.
研究人员越来越多地使用自我报告的健康状况评估方法，但这些方法需要进行验证。性能量表（PS）是一种用于评估与多发性硬化症（MS）相关残疾的自我报告测量工具，可评估运动能力、肠道/膀胱功能、疲劳、感觉、视力、认知、痉挛状态和手部功能。PS总分的效标效度已通过扩展残疾状态量表（EDSS）得以确立，但各个子量表的结构效度和效标效度尚未确立。我们评估了PS子量表的效标效度和结构效度。44例MS患者完成了PS量表以及以下效标测量：神经学检查（EDSS）、多发性硬化症功能综合量表（MSFC）、对比敏感度测试以及多发性硬化症生活质量量表。我们通过PS子量表与其他测量指标之间的Spearman等级相关性来评估效标效度和结构效度。PS与MSFC相关（r = -0.58，P < 0.0001）。运动能力、手部、视力、疲劳和膀胱功能子量表与其效标测量指标相关（r = 0.59 - 0.77，P < 0.0001）。感觉功能子量表与感觉功能系统评分的相关性较弱（r = 0.39，P = 0.01），认知子量表与PASAT不相关（r = -0.17，P = 0.26）。本研究支持PS量表整体及其运动能力、手部、视力、疲劳和膀胱功能子量表的效标效度和结构效度。需要对认知、感觉和痉挛状态子量表进行进一步评估。
