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[甲状腺降钙素对胃肠道周期性运动活动的影响]

[Influence of thyrocalcitonin on the periodic motor activity of the gastro-intestinal tract].

作者信息

Lebedev N N, Briskin A I

出版信息

Biull Eksp Biol Med. 1975 Sep;80(9):10-2.

PMID:1222261
Abstract

Experiments were conducted on dogs with fistulae of the stomach and various portions of the small intestine in which there was recorded a periodic motor activity. It was shown that intravenous injection of a highly purified bovine thyrocalcitonin (TCT) in doses of 2--10 Units/kg (considerably exceeding the doses used at the clinic in the treatment of patients with bone pathology) caused no changes in a number of indices characterizing the motor periodic activity of the stomach and various portions of the small intestine, despite a distinct reduction (by 10--20%) of the calcium level in the blood serum.

摘要

在患有胃和小肠各部位瘘管的狗身上进行了实验,记录了它们的周期性运动活动。结果表明,静脉注射高纯度牛甲状腺降钙素(TCT),剂量为2 - 10单位/千克(大大超过临床上用于治疗骨病患者的剂量),尽管血清钙水平明显降低(降低了10 - 20%),但并未引起一些表征胃和小肠各部位运动周期性活动的指标发生变化。

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1
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Biull Eksp Biol Med. 1975 Sep;80(9):10-2.
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