Zaks I O, Ivleva V V
Biull Eksp Biol Med. 1975 Sep;80(9):29-31.
Dynamics of the lactate, pyruvate, organic acid concentrations and of the L/P ratio in the blood was studied in 22 patients with massive blood loss and in 13 experimental dogs during the terminal states (bloos loss equal to 50+/-5.3 ml/kg weight) and during the post-reanimation period. Comparison of clinical and experimental data gives reasons to believe that the maximum lactate increase (70--80 mg%) during the early restorative period after clinical death does not necessarily predict the lethal issue. Nevertheless, the critical level of blood lactic acid (if the clinical death had not as yet developed) could serve as a prognostic criterion. The long-term increase in the lactate level could also serve as an unfavourable prognosis.
对22例大量失血患者和13只实验犬在终末期（失血量等于50±5.3 ml/kg体重）及复苏后期的血液中乳酸、丙酮酸、有机酸浓度以及L/P比值的动态变化进行了研究。临床和实验数据的比较使我们有理由相信，临床死亡后早期恢复阶段乳酸的最大增加量（70-80 mg%）不一定预示着致命结局。然而，血液乳酸的临界水平（如果临床死亡尚未发生）可作为预后标准。乳酸水平的长期升高也可作为不良预后的指标。
