Kusano Toshiomi, Isa Tsutomu, Tsukasa Kinjo, Sasaki Makoto, Ohtsubo Mitsuji, Furukawa Masato
First Department of Surgery, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
Int Surg. 2002 Apr-Jun;87(2):107-13.
A pancreaticobiliary maljunction (PB-MJ) without bile duct dilatation is relatively rare. The standard treatment for these patients remains controversial. In this study, we followed up the patients with PB-MJ without bile duct dilatation who mainly underwent a cholecystectomy alone. Eighteen adult patients with PB-MJ without bile duct dilatation (8 males and 10 females with a mean age of 54.8 years) were treated surgically. When the diameter of the common bile duct was less than 10 mm, such bile ducts were diagnosed to have no dilatation. The main clinical indications for surgery were cholecystolithiasis in 12 patients, choledocholithiasis in 3, cholecystocholedocholithiasis in 1, and carcinoma of the gallbladder in 2. The amylase levels of gallbladder bile in 14 patients ranged from 115 to 454,000 IU/ml. A simple cholecystectomy was performed in 12 patients, a cholecystectomy with bile duct drainage was performed in 3, a cholecystectomy with a choledochojejunostomy without bile duct resection was performed in 1, and a cholecystectomy with a lymph node dissection was performed in 2. Three patients died of other diseases. The remaining 15 patients have all been doing well for 20-209 months after surgery. In conclusion, a prophylactic resection of the extrahepatic bile duct and biliary diversion could be unnecessary for patients with PB-MJ without bile duct dilatation, when no bile stasis, such as choledocholithiasis, is observed.
无胆管扩张的胰胆管合流异常(PB-MJ)相对少见。这些患者的标准治疗方法仍存在争议。在本研究中,我们对主要仅接受胆囊切除术的无胆管扩张的PB-MJ患者进行了随访。18例无胆管扩张的成年PB-MJ患者(8例男性,10例女性,平均年龄54.8岁)接受了手术治疗。当胆总管直径小于10mm时,诊断为无胆管扩张。手术的主要临床指征为:12例患者有胆囊结石,3例有胆总管结石,1例有胆囊胆总管结石,2例有胆囊癌。14例患者胆囊胆汁淀粉酶水平在115至454,000IU/ml之间。12例患者行单纯胆囊切除术,3例行胆囊切除并胆管引流术,1例行胆囊切除、胆总管空肠吻合术但未行胆管切除术,2例行胆囊切除并淋巴结清扫术。3例患者死于其他疾病。其余15例患者术后20至209个月均情况良好。总之,对于无胆管扩张的PB-MJ患者,若未观察到胆汁淤积(如胆总管结石),则可能无需预防性切除肝外胆管并行胆肠内引流术。