伴有和不伴有胆管扩张的胰胆管合流异常的成人临床异常表现。
Clinical abnormalities in adults with pancreaticobiliary maljunction with and without bile-duct dilatation.
作者信息
Tanaka K, Nishimura A, Ishibe R, Yoshimine M, Ogata S, Taira A
机构信息
Second Department of Surgery, Kagoshima University, Faculty of Medicine, Japan.
出版信息
Can J Surg. 1995 Aug;38(4):351-4.
OBJECTIVE
To study clinical diseases associated with pancreaticobiliary maljunction with or without bile-duct dilatation.
DESIGN
A retrospective study over 16 years.
SETTING
A single university surgical service in Japan.
PATIENTS
Thirty-three patients with pancreaticobiliary maljunction.
MAIN OUTCOME MEASURES
Gallstones and cancer in patients with and without bile-duct dilatation.
RESULTS
Twenty-five patients had dilatation of the bile duct, 8 did not. Seven (28%) of the 25 patients with bile-duct dilatation had gallstones compared with 1 (12%) of the 8 patients with no dilatation. Seven (88%) of the 8 patients with no dilatation had carcinoma (all of the gallbladder), but only 3 (12%) of the 25 patients with bile-duct dilatation had carcinoma (1 of the gallbladder, 2 of the bile duct).
CONCLUSION
Prophylactic cholecystectomy is recommended for patients with pancreaticobiliary maljunction and no dilatation of the bile duct because of the high incidence of gallbladder cancer.
目的
研究合并或不合并胆管扩张的胰胆管合流异常相关的临床疾病。
设计
一项为期16年的回顾性研究。
地点
日本一所大学的单一外科科室。
患者
33例胰胆管合流异常患者。
主要观察指标
合并和不合并胆管扩张患者的胆结石和癌症情况。
结果
25例患者有胆管扩张，8例没有。25例胆管扩张患者中有7例（28%）有胆结石，而8例无扩张患者中有1例（12%）有胆结石。8例无扩张患者中有7例（88%）发生癌症（均为胆囊癌），但25例胆管扩张患者中只有3例（12%）发生癌症（1例胆囊癌，2例胆管癌）。
结论
由于胆囊癌发病率高，建议对胰胆管合流异常且无胆管扩张的患者进行预防性胆囊切除术。
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