Shin J H, Kim M J, Cho S, Whang K K, Hahm J H
Department of Dermatology, College of Medicine, Ewha Womans University, Seoul, Korea.
J Eur Acad Dermatol Venereol. 2002 Jul;16(4):384-6. doi: 10.1046/j.1468-3083.2002.00563.x.
The authors report the case of a 21-year-old woman with a giant congenital nevocytic nevus (GCNN) who developed vitiligo at the age of 16 years on skin areas remote from the GCNN. This is the first reported case of GCNN developing neurotization combined with vitiliginous changes within the GCNN lesion. Treatment with PUVA achieved repigmentation of the vitiligo lesions, except for the hypochromic areas within the area of the nevus that were shielded from UVA radiation.
作者报告了一例21岁患有巨大先天性黑素细胞痣（GCNN）的女性病例，该患者在16岁时于远离GCNN的皮肤区域出现了白癜风。这是首例报道的GCNN发生神经化并伴有GCNN皮损内白癜风样改变的病例。除了痣区域内被UVA辐射屏蔽的浅色区域外，补骨脂素加紫外线A（PUVA）治疗使白癜风皮损重新色素沉着。
