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[结核病杆菌对抗生素的初始耐药率评估中实际敏感性试验的批判性分析]

[Critical analysis of practical sensitivity tests in the evaluation of the primary resistance rate of tuberculosis bacilli to antibiotics].

作者信息

Boulahbal F, Khaled S

出版信息

Arch Inst Pasteur Alger. 1978;53:291-8.

PMID:122308
Abstract

Tuberculosis bacilli strains isolated from patients with pulmonary tuberculosis were tested to antituberculosis drugs in our laboratory since 1967 with the same method and by the same staff. However, there was a great fluctuation in the primary resistance rates calculated from one year to another and from one area to another. The analysis of strain sample showed that the main reasons were : the unprecision of patients questionnary, the preselection of strains sent to the laboratory and the unrespect of sanitary sectorisation.

摘要

自1967年起,我们实验室采用相同方法、由同一批工作人员对从肺结核患者中分离出的结核杆菌菌株进行抗结核药物检测。然而,不同年份以及不同地区计算出的原发耐药率波动很大。对菌株样本的分析表明,主要原因是:患者问卷不准确、送往实验室的菌株预先经过筛选以及未遵循卫生分区原则。

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