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捻转血矛线虫田间株对目前使用的五种苯并咪唑驱虫药的抗性

The resistance of a field strain of Haemonchus contortus to five benzimidazole anthelmintics in current use.

作者信息

Berger J

出版信息

J S Afr Vet Assoc. 1975 Dec;46(4):369-72.

PMID:1223291
Abstract

Using artificially infected sheep, the response of a laboratory strain of Haemonchus contortus, which had not been subjected to anthelmintics for three years, was compared with that exhibited by a parbendazole resistant field strain following treatment with each of seven anthelmintics, the laboratory strain proved fully susceptable to thiabendazole, parbendazole, cambendazole, mebendazole, fenbandazole, levamisole and haloxon, in contrast to the field strain which showed a moderate to marked resistance to all five benzimidazoles, but was fully susceptible to levamisole and haloxon.

摘要

利用人工感染的绵羊,将一个三年未接触过驱虫药的捻转血矛线虫实验室株系的反应,与一个对丙硫苯咪唑耐药的田间株系在用七种驱虫药中的每一种进行治疗后的反应进行比较。结果表明,实验室株系对噻苯达唑、丙硫苯咪唑、坎苯达唑、甲苯达唑、芬苯达唑、左旋咪唑和哈乐松完全敏感,而田间株系对所有五种苯并咪唑类药物表现出中度至显著抗性,但对左旋咪唑和哈乐松完全敏感。

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