MMWR Morb Mortal Wkly Rep. 2002 Jul 19;51(28):616-8.
Pertussis (i.e., whooping cough) is associated typically with an inspiratory "whoop," prolonged paroxysmal cough, and posttussive vomiting; however, persons infected with Bordetella pertussis sometimes experience atypical symptoms, making prompt recognition difficult and probably increasing infection transmission. All infants aged <6 months and any infants who have not yet received 3 doses of diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine are especially vulnerable to B. pertussis infection. This report summarizes the investigations of two pertussis deaths that occurred in 2000. Clinicians should consider pertussis as a cause of illness, especially among vulnerable infants who present with cough illness, respiratory distress, or apnea. Timely diagnosis of pertussis in caregivers and other contacts of infants could prevent infant pertussis fatalities.
百日咳通常与吸气性“吼声”、持续性阵发性咳嗽及咳嗽后呕吐有关；然而，感染百日咳博德特氏菌的人有时会出现非典型症状，这使得难以迅速识别，且可能增加感染传播。所有年龄小于6个月的婴儿以及任何尚未接种3剂白喉、破伤风类毒素及无细胞百日咳（DTaP）疫苗的婴儿尤其易感染百日咳博德特氏菌。本报告总结了2000年发生的两例百日咳死亡病例的调查情况。临床医生应将百日咳视为一种致病原因，尤其是在出现咳嗽疾病、呼吸窘迫或呼吸暂停的易感染婴儿中。及时诊断照顾婴儿的人员及其他接触者的百日咳可预防婴儿百日咳死亡。
