Gordon W C, Brennan M J, Rose R C
Pharmacol Biochem Behav. 1975 Nov-Dec;3(6):967-72. doi: 10.1016/0091-3057(75)90003-9.
Contrary to previous findings, some recent studies have reported that several daily injections of strychnine, beginning 24 hr after learning, facilitates subsequent retention. The present paper reports 3 studies using mice which suggest that strychnine has no effect on retention when the learning-injection interval is 24 hr. This absence of an effect was found using a range of strychnine doses. Furthermore, the absence of the facilitation effect was found not to be due to any failure of animals to learn prior to injection or to the fact that all animals performed asymptotically on the retention test.
与之前的研究结果相反，最近一些研究报告称，在学习后24小时开始每天注射几次士的宁，有助于后续的记忆保持。本文报告了3项以小鼠为对象的研究，结果表明，当学习与注射的间隔时间为24小时时，士的宁对记忆保持没有影响。在一系列士的宁剂量下均发现了这种无作用的情况。此外，未发现促进作用并非由于动物在注射前未能学习，也不是由于所有动物在记忆测试中都达到了极限表现。
