Roseano Mauro, Calligaris Luca, Pozzetto Barbara, Cibi Natascia, Bortul Marina
Istituto di Clinica Chirurgica Generale e Terapia Chirurgica, Cattedra di Chirurgia Geriatrica, Dipartimento Universitario Clinico di Scienze Chirurgiche Generali, Anestesiologiche e di Medicina Intensiva, Università degli Studi di Trieste.
Chir Ital. 2002 Jul-Aug;54(4):437-45.
Thorough evaluation of surgical risk represents the sine qua non for a correct therapeutic choice particularly in the elderly who are frequently affected by multiple pathologies. The aim of this study was to evaluate the prognostic value of two of the most common classification systems for predicting surgical risk (ASA and Reiss scores) and of other laboratory parameters. A consecutive series of 207 patients aged 70 or above were analysed retrospectively, considering age, ASA and Reiss scores, elective or emergency surgery, operative time, leucocytes, haemoglobin, creatinine, and albumin levels. Morbidity and mortality rates were compared in relation to these parameters. Emergency surgery was associated with significantly higher morbidity (P = 0.006 chi-square) and mortality (P = 0.001 chi-square) than elective surgery. No differences in morbidity were noted in association with the ASA classification (P = 0.07 chi-square), though there was a significant difference (P = 0.001 chi-square) in mortality. Significant differences in both morbidity (P = 0.04 chi-square) and mortality (P = 0.001 chi-square) were found to be associated with the Reiss classification. Multivariate analysis showed that ASA score (P = 0.006), Reiss score (P = 0.004), operative time (P = 0.005), and haemoglobin level (P = 0.01) were independent prognostic factors. The results of the study confirm the prognostic value of multiparametric classifications such as the ASA and Reiss score in elderly patients, even if the addition of other prognostic factors may be expected to improve the sensitivity.
全面评估手术风险是做出正确治疗选择的必要条件,尤其是在经常患有多种疾病的老年人中。本研究的目的是评估两种最常用的预测手术风险的分类系统(ASA和Reiss评分)以及其他实验室参数的预后价值。回顾性分析了连续的207例70岁及以上的患者,考虑了年龄、ASA和Reiss评分、择期或急诊手术、手术时间、白细胞、血红蛋白、肌酐和白蛋白水平。比较了与这些参数相关的发病率和死亡率。急诊手术的发病率(P = 0.006,卡方检验)和死亡率(P = 0.001,卡方检验)显著高于择期手术。与ASA分类相关的发病率无差异(P = 0.07,卡方检验),但死亡率有显著差异(P = 0.001,卡方检验)。发现发病率(P = 0.04,卡方检验)和死亡率(P = 0.001,卡方检验)的显著差异均与Reiss分类相关。多变量分析显示,ASA评分(P = 0.006)、Reiss评分(P = 0.004)、手术时间(P = 0.005)和血红蛋白水平(P = 0.01)是独立的预后因素。研究结果证实了多参数分类如ASA和Reiss评分在老年患者中的预后价值,即使预期增加其他预后因素可能会提高敏感性。