Barbero A, Blanco Y, Pulido F J
Departamento de Química Orgánica, Universidad de Valladolid, 47011 Valladolid, Spain.
Chem Commun (Camb). 2001 Sep 7(17):1606-7.
Silylcupration of allene using phenyldimethylsilylcopper 1 followed by BF3-mediated reaction with alpha,beta-unsaturated nitriles at -40 degrees C affords allylsilane-vinylsilane-containing ketones resulting from consecutive addition (1,2 and 1,4) of the intermediate allyl- and vinylcopper species formed in the silylcupration of allene.
使用苯基二甲基硅基铜1对丙二烯进行硅基铜化反应，然后在-40℃下与α,β-不饱和腈进行BF₃介导的反应，可得到含有烯丙基硅烷-乙烯基硅烷的酮，这是由丙二烯硅基铜化反应中形成的中间体烯丙基铜和乙烯基铜物种连续加成（1,2和1,4）而产生的。
