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迟发型产后子痫:一种罕见且难以诊断的病症。

Late onset postpartum eclampsia: a rare and difficult diagnosis.

作者信息

Dziewas Rainer, Stögbauer Florian, Freund Michael, Lüdemann Peter, Imai Tanya, Holzapfel Christian, Ringelstein P Bernd

机构信息

Department of Neurology, University of Münster, Albert-Schweitzer-Strasse 33, 48129 Münster, Germany.

出版信息

J Neurol. 2002 Sep;249(9):1287-91. doi: 10.1007/s00415-002-0840-z.

Abstract

Late postpartum eclampsia without the classical pre-eclamptic signs oedema, proteinuria and hypertension is a rarely noticed complication of pregnancy. In three patients eclampsia started no earlier than 6, 8 and 11 days postpartum. Seizures were preceded by headache, vomiting, visual disturbance or impaired level of consciousness. One patient suffered a series of seizures making neurointensive care necessary. In another patient the clinical course was complicated by an additional Guillain-Barré syndrome. Aside from the typical parieto-occipital lesions brain MRI showed cerebellar hyperintensities on T2 weighted sequences as well as abnormalities on diffusion weighted images in one patient. In all patients neurological deficits and MRI findings were reversible.

摘要

产后晚期子痫没有典型的先兆子痫体征(水肿、蛋白尿和高血压),是一种很少被注意到的妊娠并发症。在三名患者中,子痫分别在产后6天、8天和11天开始发作。发作前有头痛、呕吐、视觉障碍或意识水平受损。一名患者发生了一系列癫痫发作,需要进行神经重症监护。另一名患者的临床病程因并发吉兰-巴雷综合征而复杂化。除了典型的顶枕叶病变外,一名患者的脑部MRI在T2加权序列上显示小脑高信号,在弥散加权图像上也有异常。所有患者的神经功能缺损和MRI表现均可逆转。

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