Singh P J, Tobach E
Dev Psychobiol. 1975 Mar;8(2):151-64. doi: 10.1002/dev.420080207.
To determine whether bilateral olfactory bulbectomy led to a change in nursing behavior, and thus death, we bilaterally bulbectomized (BX) pups from 14 litters at 2, 7, and 11 days of age. Litters treated on Days 2 and 7 consisted of 3 BX pups, 2 surgical control (SC) pups, and 2 handling control (HC) pups. Litters treated on Day 11 consisted of 1 or 2 BX, 1 or 2 incompletely bulbectomized pups (IBX), 2 SC pups, and 2 HC pups. These litters and 3 additional nontreated litters were observed on Days 4,7,10,13, and 16. A smaller number of BX pups survived through Day 10 than SC, HC, IBX, and nontreated pups. Differential treatment of the BX pups by females or littermates was not found. The females' mammary glands were functional but the BX pup stomachs had little or no milk. The BX pups spent less time nursing and more time away from the female and their littermates than did the other pups.
为了确定双侧嗅球切除是否会导致母性行为改变，进而导致死亡，我们在幼崽2日龄、7日龄和11日龄时，对来自14窝的幼崽进行了双侧嗅球切除（BX）。在2日龄和7日龄接受处理的窝中，有3只BX幼崽、2只手术对照（SC）幼崽和2只操作对照（HC）幼崽。在11日龄接受处理的窝中，有1只或2只BX、1只或2只未完全切除嗅球的幼崽（IBX）、2只SC幼崽和2只HC幼崽。在第4、7、10、13和16天观察了这些窝以及另外3窝未处理的幼崽。到第10天时，存活的BX幼崽比SC、HC、IBX和未处理的幼崽少。未发现雌性或同窝幼崽对BX幼崽有差别对待。雌性的乳腺功能正常，但BX幼崽的胃里几乎没有或没有乳汁。与其他幼崽相比，BX幼崽用于哺乳的时间较少，与雌性及其同窝幼崽待在一起的时间较多。
