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1
Preliminary evidence for the effects of environmental complexity on hybridization of rat brain RNA to rat unique DNA.
Dev Psychobiol. 1975 Mar;8(2):171-8. doi: 10.1002/dev.420080209.
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1
Activity-dependent plasticity and gene expression modifications in the adult CNS.成人中枢神经系统中的活动依赖性可塑性和基因表达修饰。
Front Mol Neurosci. 2011 Nov 28;4:50. doi: 10.3389/fnmol.2011.00050. eCollection 2011.
2
Analysis of hippocampal RNA in rats with genetically determined differences in learning ability.对学习能力存在基因决定差异的大鼠海马RNA的分析。
Neurosci Behav Physiol. 1981 Jan-Feb;11(1):16-23. doi: 10.1007/BF01349666.

Preliminary evidence for the effects of environmental complexity on hybridization of rat brain RNA to rat unique DNA.

作者信息

Uphouse L L, Bonner J

出版信息

Dev Psychobiol. 1975 Mar;8(2):171-8. doi: 10.1002/dev.420080209.

DOI:10.1002/dev.420080209
PMID:1225692
Abstract

Hybridization to unique DNA by RNA from brain or liver of rats given varying degrees of experience was investigated. RNA from brain of environmentally enriched rats hybridized to more unique DNA than did brain RNA from nonenriched controls. No significant differences were observed with liver RNA. This provides preliminary evidence for an increased transcription of the unique sequences of DNA in the enriched animals. The technique used has great promise for the investigation of experientially-induced alterations in gene expression.

摘要