Reed R J, Meek T, Ichinose H
J Cutan Pathol. 1975;2(1):1-18. doi: 10.1111/j.1600-0560.1975.tb00825.x.
Three phases of lichenoid reactions are defined: 1) the primary phase, 2) the established phase; and 3) the senescent phase. Lichen striatus is characterized by a primary pattern that may be apparent in the epidermis, the hair follicles, and rarely the sweat glands and ducts. Focal areas of established lichenoid reaction, that are indistinguishable from lichen planus, are common. They usually are confined to the tips of elongated rete ridges. Established lichenoid patterns are occasionally present in hair follicles and are indistinguishable from those seen in lichen planopilaris. Eccrine hidradenitis, a feature of lichen striatus, is rarely seen in lichen planus. Lichen planus may be an adaptive epidermal response to a clone of aggressive lymphocytes and, as such, may be a manifestation of auto-immunity. In lichen striatus, senescent lichenoid patterns resemble those seen in lichen nitidus.
1）初期阶段；2）确立阶段；3）衰老阶段。线状苔藓的特征是初期模式，可能在表皮、毛囊中明显可见，很少出现在汗腺和导管中。与扁平苔藓难以区分的确立苔藓样反应的局灶性区域很常见。它们通常局限于延长的表皮嵴的尖端。确立的苔藓样模式偶尔出现在毛囊中，与毛发扁平苔藓中所见的模式难以区分。小汗腺炎是线状苔藓的一个特征，在扁平苔藓中很少见。扁平苔藓可能是对一群侵袭性淋巴细胞的适应性表皮反应，因此可能是自身免疫的一种表现。在线状苔藓中，衰老的苔藓样模式类似于光泽苔藓中所见的模式。
