Ansell B M, Simpson C
MRC Rheumatism Unit, Canadian Red Cross Memorial Hospital, Taplow, Buckinghamshire.
Proc R Soc Med. 1977;70 Suppl 3(Suppl 3):123-5. doi: 10.1177/00359157770700S337.
When the disease state improves during penicillamine therapy, resumption of growth occurs; if activity persists despite therapy, the expected fall-off in growth due to active Still's disease continues. Penicillamine does not interfere with the growth spurt after withdrawal of corticosteroid therapy or with the maintained slow growth during alternate-day steroid therapy.
在青霉胺治疗期间疾病状态改善时,生长会恢复;如果尽管进行了治疗疾病活动仍持续,则由于活动性斯蒂尔病导致的预期生长减缓会继续。青霉胺不会干扰停用皮质类固醇治疗后的生长突增,也不会干扰隔日类固醇治疗期间持续的缓慢生长。