Colleau Jean-Jacques
Station de génétique quantitative et appliquée, Institut national de la recherche agronomique, 78352 Jouy-en-Josas Cedex, France.
Genet Sel Evol. 2002 Jul-Aug;34(4):409-21. doi: 10.1186/1297-9686-34-4-409.
A method was described for calculating population statistics on relationship coefficients without using corresponding individual data. It relied on the structure of the inverse of the numerator relationship matrix between individuals under investigation and ancestors. Computation times were observed on simulated populations and were compared to those incurred with a conventional direct approach. The indirect approach turned out to be very efficient for multiplying the relationship matrix corresponding to planned matings (full design) by any vector. Efficiency was generally still good or very good for calculating statistics on these simulated populations. An extreme implementation of the method is the calculation of inbreeding coefficients themselves. Relative performances of the indirect method were good except when many full-sibs during many generations existed in the population.
描述了一种在不使用相应个体数据的情况下计算亲缘系数群体统计量的方法。它依赖于被调查个体与其祖先之间分子亲缘关系矩阵的逆矩阵结构。在模拟群体上观察了计算时间，并与传统直接方法的计算时间进行了比较。结果表明，间接方法在将对应于计划交配（完全设计）的亲缘关系矩阵与任何向量相乘时非常有效。对于计算这些模拟群体的统计量，效率通常仍然良好或非常好。该方法的一种极端应用是计算近交系数本身。除了群体中存在许多代的全同胞时，间接方法的相对性能良好。
