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Is the mechanism of action during treatment of rheumatoid arthritis with penicillamine and gold thiomalate the same?

作者信息

Jellum E, Aaseth J, Munthe E

机构信息

Institute of Clinical Biochemistry, Rikshospitalet, Oslo, Norway.

出版信息

Proc R Soc Med. 1977;70 Suppl 3(Suppl 3):136-9. doi: 10.1177/00359157770700S341.

Abstract
摘要

引用本文的文献

1
Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
ACS Chem Biol. 2019 Feb 15;14(2):266-275. doi: 10.1021/acschembio.8b00972. Epub 2019 Jan 24.
2
Penicillamine nephropathy.
Br Med J (Clin Res Ed). 1981 Mar 7;282(6266):761-2.
4
Prolonged treatment with D-penicillamine: effects on adjuvant arthritis in the rat.
Agents Actions. 1984 Feb;14(2):269-73. doi: 10.1007/BF01966652.
5
Free thiomalate in plasma and urine of patients receiving sodium aurothiomalate.
Ann Rheum Dis. 1984 Feb;43(1):66-9. doi: 10.1136/ard.43.1.66.
6
Oral gold for rheumatoid arthritis.
Br Med J (Clin Res Ed). 1984 Oct 6;289(6449):858-9. doi: 10.1136/bmj.289.6449.858.
7
Inhibition of lymphocyte activation by gold sodium thiomalate.
Br J Pharmacol. 1983 Jun;79(2):617-22. doi: 10.1111/j.1476-5381.1983.tb11037.x.
8
Chrysotherapy and thrombocytopenia.
Ann Rheum Dis. 1985 Sep;44(9):589-91. doi: 10.1136/ard.44.9.589.
9
Pharmacokinetics of gold sodium thiomalate in rabbits.
Pharm Res. 1987 Aug;4(4):332-6. doi: 10.1023/a:1016453421958.

本文引用的文献

1
Transport of gold in the body.
Ann Rheum Dis. 1969 Jul;28(4):437-42. doi: 10.1136/ard.28.4.437.
2
Mercaptodextran, a metal-chelating and disulphide-reducing polythiol of high molecular weight.
Biochem Pharmacol. 1973 May 15;22(10):1179-88. doi: 10.1016/0006-2952(73)90235-9.
3
The interaction of aurothiomalate and cysteine.
Biochem Pharmacol. 1976 Nov 1;25(21):2343-6. doi: 10.1016/0006-2952(76)90025-3.

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