Wünschmann Arno, Frank Rodney, Pomeroy Kem, Kapil Sanjay
Department of Veterinary Diagnostic Medicine, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA.
J Vet Diagn Invest. 2002 Sep;14(5):441-4. doi: 10.1177/104063870201400518.
A case of an enteric coronavirus infection in a 6-week-old dromedary calf is described. The animal had diarrhea for 5 days and died despite symptomatic treatment. Numerous viral particles, approximately 140 nm in diameter, with club-like projections were detected in the feces by electron microscopy. These characteristics were consistent with a coronavirus. Immunohistochemical reactivity with 2 antigenic group II coronavirus-specific antibodies confirmed the presence of viral antigen in colonic epithelial cells. The death of the animal was attributed to a neutrophilic and emphysematous colitis that likely was caused by an infection with a Clostridium sp.
描述了一例6周龄单峰骆驼犊牛感染肠道冠状病毒的病例。该动物腹泻5天,尽管进行了对症治疗仍死亡。通过电子显微镜在粪便中检测到大量直径约140纳米、带有棒状突起的病毒颗粒。这些特征与冠状病毒一致。用2种抗原性II组冠状病毒特异性抗体进行免疫组织化学反应,证实结肠上皮细胞中存在病毒抗原。该动物的死亡归因于可能由梭菌属感染引起的嗜中性粒细胞性和肺气肿性结肠炎。