圣多美和普林西比（西非）冈比亚按蚊（双翅目：蚊科）的遗传结构：对疟疾控制的影响

Genetic structure of Anopheles gambiae (Diptera: Culicidae) in São Tomé and Príncipe (West Africa): implications for malaria control.

作者信息

Pinto J, Donnelly M J, Sousa C A, Gil V, Ferreira C, Elissa N, do Rosário V E, Charlwood J D

机构信息

Centro de Malária e outras Doenças Tropicais, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa. Rua da Junqueira 96 1349-008 Lisbon, Portugal.

出版信息

Mol Ecol. 2002 Oct;11(10):2183-7. doi: 10.1046/j.1365-294x.2002.01587.x.

DOI:10.1046/j.1365-294x.2002.01587.x

PMID:12296959

Abstract

The impact of a vector eradication programme, conducted in the 1980s, on Anopheles gambiae populations from the islands of São Tomé and Príncipe, was evaluated by microsatellite DNA analysis. Significant genetic differentiation was observed within and between the two islands and between the islands and a population from Gabon, suggesting a degree of isolation between them. Large estimates of long-term N(e) suggested that the control programme did not affect the effective population size of the vector. Heterozygosity tests were also not consistent with a recent bottleneck.

摘要

通过微卫星DNA分析评估了20世纪80年代开展的病媒根除计划对圣多美和普林西比岛冈比亚按蚊种群的影响。在两个岛屿内部和之间以及岛屿与加蓬的一个种群之间观察到显著的遗传分化，表明它们之间存在一定程度的隔离。对长期有效种群大小（N(e)）的大量估计表明，控制计划并未影响病媒的有效种群大小。杂合性测试也与近期的瓶颈现象不一致。