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[角叉菜胶诱导炎症中的组织化学方面]

[Histochemical aspects in carrageenan induced inflammation].

作者信息

Weischer C H

出版信息

Arch Exp Veterinarmed. 1975;29(5):769-76.

PMID:1230107
Abstract

Some changes of groundsubstance and cell proliferation are histochemically demonstrated in the carrageenin induced edema, in the connective tissue of the rat hund paw. We observed, that the leucocytic infiltration (beginning 5 minutes after inflammation) and the desintegration of these cells, induced by liberated lysosomal enzymes, can be assumed to be connected with mastcell degeneration. Fibroblasts and mastcells are correlating in the phase of woundhealing. Iron, which is found in the phagocytes of the connective tissue, in the acute stage of inflammation may not only be a consequence of the desintegration of erythrocytes, its appearance could be interpreted as support of the hypothesis of its antitoxic function.

摘要

在角叉菜胶诱导的大鼠后爪结缔组织水肿中,通过组织化学方法证实了基质和细胞增殖的一些变化。我们观察到,白细胞浸润(炎症开始后5分钟)以及由释放的溶酶体酶诱导的这些细胞的解体,可以假定与肥大细胞变性有关。成纤维细胞和肥大细胞在伤口愈合阶段相互关联。在炎症急性期,结缔组织吞噬细胞中发现的铁,可能不仅是红细胞解体的结果,其出现也可被解释为支持其抗毒功能假说。

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