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儿童肝血吸虫病的钙磷代谢变化

Calcium and phosphorus metabolic changes in children with hepatic bilharziasis.

作者信息

Hafez M, Mohareb S W, Hafez T A, Fahmi H A, Kassem A S, El Nahhas M R, El-Nady A

出版信息

Gaz Egypt Paediatr Assoc. 1975 Jul-Oct;23(3-4):243-52.

PMID:1230349
Abstract

Investigations were done to study the calcium and phosphorus metabolic changes in 35 children with hepatic bilharziasis, of whom 12 were ascitic. Thirteen normal children served as controls. Despite a normal serum level of both calcium and inorganic phosphate in the Bilharzial group, yet both were increased in urine. The mean values obtained from the ascitic fluid were 70% and 90.2% of their serum levels, respectively. The corrected creatinine clearance was significantly diminished, while PEI was significantly increased, and the % TRP significantly decreased, with still a more marked decrease in the ascitic cases. Following a phosphate lead the serum inorganic phosphate level showed a significantly more rapid lowering in both bilharzial groups, as compared to the control group. On the other hand bilharzial cases responded to the intravenous calcium load by a significant retention of calcium in the serum.

摘要

对35例肝血吸虫病患儿进行了研究,以探讨其钙磷代谢变化,其中12例有腹水。13名正常儿童作为对照。尽管血吸虫病组血清钙和无机磷水平正常,但两者在尿中均升高。腹水中钙和无机磷的平均值分别为血清水平的70%和90.2%。校正肌酐清除率显著降低,而磷排泄指数显著升高,可滴定酸百分比显著降低,腹水患儿降低更明显。给予磷负荷后,与对照组相比,两个血吸虫病组血清无机磷水平下降明显更快。另一方面,血吸虫病患儿静脉注射钙负荷后,血清钙显著潴留。

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