Habib Y A, Kira L H, el-Sherbini H A, Asser L A, el-Shamy E A, Hatem Y A
Department of Physiology and Tropical Medicine, Faculty of Medicine, Alexandria, Egypt.
J Trop Med Hyg. 1991 Aug;94(4):272-6.
Fifty subjects divided into three groups were studied: Group I: 10 normal adult subjects as controls. Group II: 20 patients with schistosomal hepatic fibrosis (SHF) without ascites (compensated stage). Group III: 20 patients with SHF with ascites. In all these patients plasma atrial natriuretic factor (ANF), serum aldosterone and serum osmolality were determined. There was a significant decrease in the plasma ANF in groups II and III compared to group I. There was a significant increase in the serum aldosterone level in group III compared to groups I and II. No significant difference was noted in serum sodium and potassium levels among the three groups. There was a significant decrease in serum osmolality in groups II and III compared to group I.
第一组：10名正常成年受试者作为对照组。第二组：20例无腹水的血吸虫性肝纤维化（SHF）患者（代偿期）。第三组：20例有腹水的SHF患者。对所有这些患者测定了血浆心钠素（ANF）、血清醛固酮和血清渗透压。与第一组相比，第二组和第三组的血浆ANF显著降低。与第一组和第二组相比，第三组的血清醛固酮水平显著升高。三组之间血清钠和钾水平无显著差异。与第一组相比，第二组和第三组的血清渗透压显著降低。
