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急性心肌梗死时室内阻滞的预后意义(作者译)

[Prognostic significance of the intraventricular blocks during acute myocardial infarction (author's transl)].

作者信息

Fazzini P F, Marchi F, Pucci P

出版信息

G Ital Cardiol. 1975;5(4):526-35.

PMID:1232014
Abstract

An intraventricular conduction defect complicated 39 out of 489 cases of acute myocardial infarctions. The defect, with the exception of one case, always developed in infarctions in the anterior wall of the heart. Compared with the other acute anterior myocardial infarctions in which the mortality in the Coronary Care Unit was 15%, infarctions complicated by intraventricular conduction defects have on the whole, presented a worse clinical course and a higher mortality rate (56%). It must be stressed that clinical course and mortality rate have been very different in the various conduction defects. The most innocuous conduction defects were the left anterior hemiblock, and, with some reservation, the right bundle branch block too, -- defects in which the clinical course and the mortality rate were not significantly different from those of the other anterior myocardial infarctions not complicated by intraventricular conduction troubles. On the contrary clinical course was more serious and mortality rate higher (50%) in the cases in which the two defects were associated. Myocardial infarctions complicated by left bundle branch block, right bundle branch block with left posterior hemiblock, alternating bundle branch block or 1 degrees and 2 degrees atrioventricular block and bundle branch block, presented an extremely serious clinical course and a very high mortality rate (83%). These differences in the clinical course and in the mortality rate of the various intraventricular conduction defects are explained by the fact that they are associated with myocardial damage of different degree, which is clarified by knowledge of the blood supply of the intraventricular conduction system.

摘要

489例急性心肌梗死患者中有39例并发室内传导阻滞。除1例之外,这种阻滞均发生于心脏前壁梗死。与冠心病监护病房死亡率为15%的其他急性前壁心肌梗死相比,并发室内传导阻滞的梗死总体上临床过程更差,死亡率更高(56%)。必须强调的是,不同的传导阻滞其临床过程和死亡率差异很大。最无害的传导阻滞是左前半阻滞,以及在一定程度上的右束支阻滞,这些阻滞的临床过程和死亡率与未并发室内传导问题的其他前壁心肌梗死相比无显著差异。相反,两种阻滞并存的病例临床过程更严重,死亡率更高(50%)。并发左束支阻滞、右束支阻滞合并左后半阻滞、交替束支阻滞或一度及二度房室阻滞和束支阻滞的心肌梗死临床过程极其严重,死亡率非常高(83%)。各种室内传导阻滞在临床过程和死亡率上的这些差异可由以下事实解释,即它们与不同程度的心肌损伤相关,而这可通过了解室内传导系统的血供得以阐明。

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