Harris L E, Stayura L A, Ramirez-Talavera P F, Annegers J F
Mayo Clin Proc. 1975 Feb;50(2):85-90.
This report records the congenital and acquired abnormalities observed during the first 4 days of life in 21,142 live-born infants. Gross abnormalities observed in 300 stillborns also are recorded. The abnormalities are those thought to be of clinical or possibly clinical significance. Also included are other conditions ordinarily not considered to be a congenital abnormality, such as convulsions. Definitions are given when indicated. The incidence rates per 1,000 births for specific malformation noted in the first 4 days of life are provided for all births, for live births, for live births under 2,500 g, and for stillbirths. The need for accurate studies of specific forms of congenital malformations is reiterated. The rate for all malformations combined is not given since it is difficult to interpret or use for comparisons because of variations in the definition of malformation and in completeness of ascertainment in different studies.
本报告记录了21142例活产婴儿出生后头4天内观察到的先天性和后天性异常情况。同时也记录了在300例死产儿中观察到的明显异常。这些异常被认为具有临床意义或可能具有临床意义。还包括其他通常不被视为先天性异常的情况，如惊厥。在需要时给出了定义。提供了所有出生、活产、体重低于2500克的活产以及死产中，出生后头4天内特定畸形的每1000例出生发病率。重申了对特定形式先天性畸形进行准确研究的必要性。由于不同研究中畸形定义和确诊完整性存在差异，难以解释或用于比较，因此未给出所有畸形合并的发病率。
