Chassard J L, Dutou L, Gérard J P, Papillon J
Neurochirurgie. 1975 Sep-Oct;21(5):377-89.
We are dealing here with a series of 134 hemispheric gliomas of the adult subject submitted to irradiation after surgical exeresis. The 2 years survival rate reaches 51 p. 100 for stage I and II astrocytomas (15/29) and 3,3 p. 100 for glioblastomas (30/91), the I year survival rate for the latter ones reaching 33 p. 100. The analytic study of medical literature lets appear that if roentgentherapy remains controverted in the case of stage I and II astrocytomas, it is recognized as useful, by all the authors, in the glioblastomas. Modalities and technique of the irradiation are object of an analytic study. Authors are favourable to post-operative irradiation stage I and II astrocytomas exhibiting pejorative features (focalized 6.000 to 6.500 rads) and to systematic post-operative irradiation in the glioblastomas over extended fields, either spreaded on irradiation (6.000 rads) or concentrated irradiation (two series of 1.800 rads). This latter technique has provided identical results as the spreaded on irradiation and represents a less heavy procedure. Mention is made of roentgentherapy in the supratentorial ependymomas (3 cases) and in the oligodendrogliomas (6 cases), followed by an analytic study of the complications consecutive to roentgentherapy of the encephalic tumors.
我们在此研究的是134例成年患者的半球胶质瘤,这些患者在手术切除后接受了放疗。I期和II期星形细胞瘤(15/29)的2年生存率达到51%,胶质母细胞瘤(30/91)的2年生存率为3.3%,后者的1年生存率为33%。对医学文献的分析研究表明,如果在I期和II期星形细胞瘤病例中,放射治疗仍存在争议,那么所有作者都认为它在胶质母细胞瘤中是有用的。放疗的方式和技术是一项分析研究的对象。作者们赞成对具有不良特征的I期和II期星形细胞瘤进行术后放疗(局部剂量为6000至6500拉德),并赞成对胶质母细胞瘤在扩大野上进行系统性术后放疗,要么采用分次放疗(6000拉德),要么采用集中放疗(两系列,每次1800拉德)。后一种技术与分次放疗提供了相同的结果,且操作负担较小。文中提到了幕上室管膜瘤(3例)和少突胶质细胞瘤(6例)的放射治疗,随后对脑肿瘤放射治疗后的并发症进行了分析研究。