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[不同物种辐射对雄性小鼠生殖细胞的诱变作用。VIII. 慢性γ辐射小鼠精原细胞中相互易位的发生频率]

[Mutagenic effect of irradiating different species on the sex cells of male mice. VIII. Frequency of development of reciprocal translocations in the spermatogonia of mice subjected to chronic gamma-irradiation].

作者信息

Pomerantseva M D, Vilkina G A, Ivanov V N

出版信息

Genetika. 1975;11(3):81-6.

PMID:1234115
Abstract

The frequency of reciprocal translocations in mice spermatogonia after the exposure to chronic gamma-irradiation at doses of 100, 200, 300, 600, 920 r, at the dose rate of 4,2 r/day was investigated. It was shown that the mutation frequency increased insignificantly with the increase of the radiation dose (y = 0,8+0,0011 x). The comparison of the data obtained with earlier results revealed no changes in the yield of translocations at the reduction of the dose rate from 10 r/day to 4,2 r/day. The investigation of the genetic radiosensitivity of mice spermatogonia after a chronic gamma-irradiation showed a tendency to increase in their radioresistance.

摘要

研究了小鼠精原细胞在剂量率为4.2伦琴/天,分别接受100、200、300、600、920伦琴慢性γ射线照射后的相互易位频率。结果表明,随着辐射剂量增加,突变频率无显著增加(y = 0.8 + 0.0011x)。将所得数据与早期结果比较发现,剂量率从10伦琴/天降至4.2伦琴/天时,易位发生率无变化。对小鼠精原细胞进行慢性γ射线照射后的遗传放射敏感性研究表明,其抗辐射能力有增加的趋势。

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