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低剂量率连续照射的细胞遗传学和遗传学效应。

Cytogenetic and genetic effects of continuous irradiation at a low exposure rate.

作者信息

Brezáni P, Kalina I

出版信息

Folia Biol (Praha). 1980;26(5):298-303.

PMID:7439465
Abstract

We followed the frequency of chromosome aberrations in bone marrow cells of mice continuously irradiated from a 60Co source at an exposure rate of 4.785 mGy/day (0.5R/day) for 140 days. The frequency of chromosome aberrations increased to 4.8% already at day 10 of irradiation and was stabilized at 2--3% in the period from 60 to 140 days. No increase in the frequency of reciprocal translocations and dominant lethal mutations induced in spermatogonia during irradiation was, however, observed.

摘要

我们跟踪了以4.785毫戈瑞/天（0.5伦琴/天）的照射率从60钴源连续照射140天的小鼠骨髓细胞中染色体畸变的频率。染色体畸变频率在照射第10天就已增至4.8%，并在60至140天期间稳定在2%至3%。然而，未观察到照射期间精原细胞中相互易位和显性致死突变频率的增加。

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Cytogenetic and genetic effects of continuous irradiation at a low exposure rate.低剂量率连续照射的细胞遗传学和遗传学效应。
Folia Biol (Praha). 1980;26(5):298-303.
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[Mutagenic effect of different types of radiation on the sex cells of male mice. VIII. Frequency of development of reciprocal translocations in the spermatogonia of mice subjected to chronic gamma radiation].[不同类型辐射对雄性小鼠生殖细胞的诱变作用。VIII. 受慢性γ辐射的小鼠精原细胞中相互易位的发生频率]
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[Mutagenic effect of radiation on mice subjected to gamma irradiation during the embryonic period. I. Frequency of reciprocal translocations in the spermatocytes of mice subjected to gamma-irradiation at different stages of embryogenesis].[辐射对胚胎期接受γ射线照射的小鼠的诱变作用。I.胚胎发育不同阶段接受γ射线照射的小鼠精母细胞中相互易位的频率]
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[Chromosome modifications induced in mouse spermatogonia through exposure to high-energy neutrons].[通过暴露于高能中子在小鼠精原细胞中诱导的染色体修饰]
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Cytogenetic Alterations in Preimplantation Mice Embryos Following Male Mouse Gonadal Gamma-irradiation: Comparison of Two Methods for Reproductive Toxicity Screening.雄性小鼠性腺γ射线照射后植入前小鼠胚胎的细胞遗传学改变：两种生殖毒性筛选方法的比较
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