Wilkinson S P, Portmann B, Hurst D, Williams R
Postgrad Med J. 1975 Aug;51(598):503-5. doi: 10.1136/pgmj.51.598.503.
Acute renal failure in cirrhosis and fulminant hepatic failure represents a spectrum with ‘functional renal failure’ at one end and acute tubular necrosis at the other. In fulminant hepatic failure the development of renal failure is not necessarily a measure of the severity of liver damage. Functional renal failure is due to active renal vasoconstriction which may, at least in fulminant hepatic failure, be initiated by systemic endotoxaemia.
肝硬化和暴发性肝衰竭中的急性肾衰竭代表了一个范围，一端是“功能性肾衰竭”，另一端是急性肾小管坏死。在暴发性肝衰竭中，肾衰竭的发生不一定是肝损伤严重程度的指标。功能性肾衰竭是由于肾血管主动收缩所致，至少在暴发性肝衰竭中，可能由全身性内毒素血症引发。
