Feng Yunjiang, Blunt John W, Cole Anthony L J, Munro Murray H G
Department of Chemistry, University of Canterbury, Private Bag 4800, Christchurch, New Zealand.
J Nat Prod. 2002 Sep;65(9):1274-7. doi: 10.1021/np020159k.
Fermentation of Pseudeurotium zonatum led to the isolation of the known cytochalasin G (1) and three new cytochalasins, X, Y, and Z (2-4). These four compounds are the only naturally occurring cytochalasins reported to date that contain an indole-substituted perhydroisoindol-1-one fused with an 11-membered macrocycle.
对环带拟青霉进行发酵,从中分离出了已知的细胞松弛素G(1)以及三种新的细胞松弛素,X、Y和Z(2 - 4)。这四种化合物是迄今为止报道的仅有的天然存在的细胞松弛素,它们含有一个与11元大环稠合的吲哚取代的全氢异吲哚-1-酮。