Simons M J
Am J Med Sci. 1975 Sep-Oct;270(2):349-54. doi: 10.1097/00000441-197509000-00017.
In several countries where there is a high prevalence of HBV the risk of PTH has been investigated. One study demonstrated that HBV immunity provided protection against infection following transfusion of HBs Ag-postive blood in that a higher proportion of immune recipients failed to develop, or developed only transitory, HBs antigenemia, Forty (61 per cent) of 66 recipients who received HBs Ag positive (IAHA) units developed hepatitis, which was subclinical in 37 (93 per cent) of the 40. Six recipients of HBs Ag-containing units had HBs Ag in the pre-transfusion serum. In four, HBs Ag disappeared in the early post-trasfusion period, and anti-HBs was detected within days, persisting for the duration of the study. The mechanism of this change in HBV immune status is unknown but it may be related to the existence of HBs Ag immune complexemia detectable by radioelectro-complexing in approximately 80 per cent of Hbs Ag-positive blood donors. The phenomenon of apparent "cure" of the HBs antigenemic state warrants further attention.
在几个乙肝病毒（HBV）高流行率的国家，已经对输血后肝炎（PTH）的风险进行了调查。一项研究表明，HBV免疫能为输注乙肝表面抗原（HBs Ag）阳性血液后的感染提供保护，因为更高比例的免疫接受者未能发生，或仅发生短暂的HBs抗原血症。在接受了66个HBs Ag阳性（免疫吸附血凝测定法）单位的66名接受者中，有40名（61%）发生了肝炎，其中37名（93%）为亚临床肝炎。6名接受含HBs Ag单位输血的接受者在输血前血清中就有HBs Ag。在4名接受者中，HBs Ag在输血后早期消失，且在数天内检测到抗-HBs，并在研究期间持续存在。HBV免疫状态这种变化的机制尚不清楚，但可能与约80%的HBs Ag阳性献血者中可通过放射电络合检测到的HBs Ag免疫复合物血症的存在有关。HBs抗原血症状态明显“治愈”的现象值得进一步关注。
