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[乙肝表面抗原血症献血者所献血液受血者的肝炎感染风险]

[Risk of hepatitis infection of the recipients of blood from donors with HBs-antigenemia].

作者信息

Paktoris E A, Khukhlovich P A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1982 May(5):37-41.

PMID:7102180
Abstract

Observations were made on 100 recipients of blood from 40 donors with HBs-antigenemia and 106 recipients of the control group, who had received 570 ampules of blood from 491 donors, and 499 ampules from 400 donors, respectively. The incidence of post-transfusion serum hepatitis in the icteric forms was 12.7% and 1.9%, respectively (P less than 0.002), varying between 8.9% and 22.2% in the experimental subgroups, and decreasing with the increase of the total number of blood transfusions received by the subjects. The source of infection proved to be 0.5% of the donors in the control group, and 2.65% in the experimental group (P less than 0.01), or 17.9-33.3%, of donors with HBs-antigenemia. With the sufficient number of recipients traced to each donor, all donors with HBs-antigenemia were found to be the sources of infection. It means that HBs-antigenemia may be regarded as the indication of the presence of the complete (infective) hepatitis virus B in the body.

摘要

对来自40名乙肝表面抗原血症供血者的100名受血者以及对照组的106名受血者进行了观察,对照组分别接受了来自491名供血者的570瓶血液和来自400名供血者的499瓶血液。黄疸型输血后血清性肝炎的发病率分别为12.7%和1.9%(P小于0.002),在各试验亚组中为8.9%至22.2%不等,并随着受血者接受输血总量的增加而降低。感染源在对照组供血者中为0.5%,在试验组中为2.65%(P小于0.01),在乙肝表面抗原血症供血者中为17.9%至33.3%。当追踪到每位供血者的受血者数量足够时,所有乙肝表面抗原血症供血者均被发现为感染源。这意味着乙肝表面抗原血症可被视为体内存在完整(传染性)乙型肝炎病毒的指征。

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