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一起与被单核细胞增生李斯特菌污染的熟食肉类相关的发热性肠胃炎暴发。

An outbreak of febrile gastroenteritis associated with delicatessen meat contaminated with Listeria monocytogenes.

作者信息

Frye Douglas M, Zweig Rachael, Sturgeon Joan, Tormey Michael, LeCavalier Michelle, Lee Irene, Lawani Leonard, Mascola Laurene

机构信息

Acute Communicable Disease Control Unit, Los Angeles County Department of Health Services/Public Health, Los Angeles, CA 90005, USA.

出版信息

Clin Infect Dis. 2002 Oct 15;35(8):943-9. doi: 10.1086/342582. Epub 2002 Sep 23.

Abstract

In June 2001, the Los Angeles County Department of Health Services/Public Health conducted a cohort study of an outbreak of acute febrile gastroenteritis among 16 of 44 healthy attendees of a catered party. The median age of the attendees who became ill was 15.5 years. Symptoms included body aches (in 88% of attendees), fever (81%), headache (81%), diarrhea (63%), and vomiting (56%). Illness was associated with ingestion of precooked, sliced turkey (P=.000004). Six stool specimens yielded Listeria monocytogenes. Leftover turkey yielded L. monocytogenes, 1.6x10(9) cfu/g. All isolates were serotype 1/2a and had matching molecular fingerprints. Clusters of suspect cases were identified among attendees at 2 other catered events, but no additional cases were confirmed. This is only the third reported outbreak of L. monocytogenes-associated gastroenteritis in the United States. In cases of febrile gastroenteritis for which routine cultures for enteric pathogens are negative, clinicians should suspect listeriosis and should consider asking laboratories to retain stool specimens to expedite testing for Listeria organisms.

摘要

2001年6月,洛杉矶县卫生服务部/公共卫生部对一次餐饮派对上44名健康参与者中的16人爆发的急性发热性肠胃炎进行了队列研究。发病参与者的年龄中位数为15.5岁。症状包括身体疼痛(88%的参与者)、发热(81%)、头痛(81%)、腹泻(63%)和呕吐(56%)。发病与食用预煮切片火鸡有关(P = 0.000004)。六份粪便标本检测出单核细胞增生李斯特菌。剩余火鸡检测出单核细胞增生李斯特菌,含量为1.6×10⁹ 菌落形成单位/克。所有分离株均为1/2a血清型,且分子指纹匹配。在另外两次餐饮活动的参与者中发现了疑似病例聚集,但未确诊其他病例。这是美国报告的第三起与单核细胞增生李斯特菌相关的肠胃炎疫情。对于肠道病原体常规培养呈阴性的发热性肠胃炎病例,临床医生应怀疑李斯特菌病,并应考虑要求实验室保留粪便标本,以便加快对李斯特菌的检测。

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